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Btg2 cancer

WebJun 16, 2010 · BTG2 is known to mediate chemotherapy induced apoptosis in cancer cells [29–31] and a study by Lim et al. indicates that BTG2 enhances cancer cell death by accumulation of H 2 O 2 . Down-regulation of BTG2 has been observed in several cancer types such as prostate cancer, breast cancer and gliomas [17, 18, 33]. In this study … WebBTG2 expression was elevated upon IR exposure, in a dose-dependent but not a time-dependent manner. CCK-8 and EDU assays revealed that BTG2 overexpression …

BTG2 suppresses cancer cell migration through inhibition of Src …

WebMar 21, 2024 · Elevated BTG2 improves the radiosensitivity of non-small cell lung cancer (NSCLC) through apoptosis. Zhu C, et al.Thorac Cancer, 2024 May. PMID 35388633, Free PMC Article MicroRNA miR-92a-3p regulates breast cancer cell proliferation and metastasis via regulating B-cell translocation gene 2 (BTG2). Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the precursors of cerebellar granule neurons. This demonstration was … See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with Pax6 and Tbr2 when observing the role of Tis21 in neurogenic divisions. See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more the medtech conference https://technologyformedia.com

TINCR inhibits the proliferation and invasion of laryngeal ... - BMC Cancer

WebNov 2, 2024 · BTG2 expression was significantly suppressed in human HCC compared to adjacent non-cancerous tissues. BTG2 expression was correlated with TNM stage, … WebJun 22, 2024 · 4 Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, Jiangsu, ... Knockdown of KIAA1429 significantly decreased the m6A levels of BTG2 mRNA, leading to enhanced YTH m6A RNA binding protein 2 (YTHDF2, … WebBTG2. Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene ( B -cell t ranslocation g ene 2) [5] and in other mammals by the homologous Btg2 gene. [6] [7] This protein controls cell cycle progression and proneural ... how to create peace in the world

Growth hormone promotes hepatic gluconeogenesis by enhancing BTG2…

Category:Tumor suppressors BTG1 and BTG2: Beyond growth control

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Btg2 cancer

Mol Cancer 贴壁悬浮转化促进癌症转移扩散：相关分子有望成为 …

WebBTG2 can improve the radiosensitivity of breast cancer cells by affecting cell cycle distribution, enhancing radiation-induced apoptosis, and inhibiting DNA repair-related … WebBTG2 treatment exhibited inhibitory effect on PI3K/Akt pathway in MCF-7/ADR cells. Significance miR-27a-3p might be associated with resistance of breast cancer cells to adriamycin treatments, modulating cell proliferation and apoptosis by targeting BTG2 and promoting the PI3K/Akt pathway in breast cancer cells. miR-27a-3p/BTG2 axis might be …

Btg2 cancer

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WebTherefore, BTG2 is considered to be a novel tumor suppressor gene for many types of cancer, such as laryngeal cancer [10] gastric cancer [11], liver cancer and breast cancer [12]. WebMar 7, 2024 · IntroductionLung adenocarcinoma (LUAD), as the most frequent pathological subtype of non−small cell lung cancer, is often characterized by poor prognosis and low 5-year survival rate. Exploriton of new biomarkers and accurate molecular mechanisms for effectively predicting the prognosis of LUAD patients is still necessary. Presently, BTG2 …

WebRelationship Between BTG2 Expression and Clinicopathological Factors in LUAD. Next, we evaluated the correlations between BTG2 expression and the clinicopathological factors (cancer stages, status of lymph node metastasis (LNM), age, gender, smoking habits, race). Results from the UALCAN database showed that the BTG2 expression was significantly … WebPTEN activity inhibitor (VO-OHpic) treatment decreased BTG2 expression in RT-4 and PTEN-overexpressed T24 cells. Our results suggested that BTG2 functioned as a bladder cancer tumor suppressor gene, and was induced by p53 and PTEN. Modulation of BTG2 expression seems a promising way to treat human bladder cancer.

WebMultivariate Cox proportional hazard regression analysis revealed that BTG2 mutations dominated the death risk of PT-DLBCL patients, with hazard ratios in the range of 95% CI 1.15 to 4.3311 (HR, 2.23, P =0.007). The median OS was 28 months in the BTG2 mutation group and 65 months in the BTG2 wt group ( Figure 6A ). WebTIS21 /BTG2-induced pAKT S473 required Rictor-bound mTOR kinase, indicating activation of mTORc2 by TIS21 /BTG2 gene. Additionally, the TIS21 /BTG2-induced pAKT S473 …

WebB‑cell translocation gene 2 (BTG2) is a tumor suppressor gene, which belongs to the anti‑proliferation gene family. Our previous study demonstrated that microRNA …

WebJun 29, 2024 · A study showed that BTG2 expression is downregulated in hepatocellular carcinoma and that it suppressed stem cell-like characteristics adjacent to cancer . As early as 2010, a study found that in LSCC, BTG2 was downregulated, and miR-21 could target and inhibit the expression of BTG2 and thereby inhibit its promotion of growth, … how to create percentage circle in pptWebBTG2 is a tumor suppressor gene. It is frequently downregulated in human cancer tissues, and its loss is associated with cancer cell metastasis, suggesting that the suppression of … how to create people in little alchemy 2WebFeb 21, 2011 · To analyze the role of BTG2 in breast cancer progression, BTG2 expression was knocked down in mammary epithelial cells. Suppression of BTG2 enhances the … how to create people album on iphoneWebIn addition, we found that BTG2 knockdown significantly increased the in vitro migration of A2780 and SKOV-3 ovarian cancer cells, and BTG2 overexpression inhibited the migration of ovarian cancer cells, as shown in Figure 4D. These results confirmed that BTG2 acted as a tumor suppressor in ovarian cancer. the medullary shaft is filled withWebApr 12, 2024 · AST（Adherent-to-Suspension Transition）： 贴壁到悬浮的转化，通过定义的造血转录调节因子将贴壁细胞重新编程为悬浮细胞。. 近日，韩国延世大学医学院的研究人员 Hyunbin D. Huh, Yujin Sub, Jongwook Oh, Ye Eun Kim 等人在国际知名期刊 Molecular Cancer 上发表了题为 “Reprogramming ... the medtech conference 2022 bostonWebSep 23, 2024 · BTG2 and YY1 may be crucial therapeutic targets to intervene in metabolic dysfunction in response to the GH-dependent signaling pathway. ... J. A. et al. Inhibition of breast cancer invasion by ... how to create percentage in power biWebJun 16, 2010 · BTG2 is known to mediate chemotherapy induced apoptosis in cancer cells [29–31] and a study by Lim et al. indicates that BTG2 enhances cancer cell death by … how to create percentage graph in excel